ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-M0301	Ald-Ph-PEG4-t-butyl ester	1807518-64-4		453.5	95%		Inquiry
ADC-L-M0302	Ald-Ph-PEG6-t-butyl ester	2055013-49-3		541.6	95%		Inquiry
ADC-L-M0304	Ald-Phenyl-PEG5-t-butyl ester	1433996-83-8		426.5	95%		Inquiry
ADC-L-M0305	Ald-CH2-PEG4-t-butyl ester	1415329-20-2		320.4	95%		Inquiry
ADC-L-M0306	Ald-CH2-PEG5-t-butyl ester	1446282-23-0		364.4	95%		Inquiry
ADC-L-M0307	Ald-CH2-PEG10-t-butyl ester	2353410-05-4		584.7	95%		Inquiry
ADC-L-M0308	Ald-CH2-PEG4-CH2CO2tBu	2100306-54-3		306.4	95%		Inquiry
ADC-L-M0309	Ald-Ph-PEG2-amine TFA salt	2055013-56-2		280.3	95%		Inquiry
ADC-L-M0311	Ald-PEG4-azide	2030118-14-8		275.3	95%		Inquiry
ADC-L-M0313	Ald-CH2-PEG5-azide	1446282-38-7		305.3	95%		Inquiry
ADC-L-M0314	Ald-CH2-PEG8-azide	2353410-13-4		437.5	95%		Inquiry
ADC-L-M0316	Ald-Ph-PEG2-NH-Boc	1807503-90-7		380.4	95%		Inquiry
ADC-L-M0319	Azido-PEG1-CH2CO2H	79598-48-4		145.1	95%		Inquiry
ADC-L-M0320	Azido-PEG2-CH2CO2H	882518-90-3		189.2	95%		Inquiry
ADC-L-M0321	Azido-PEG3-CH2CO2H	172531-37-2		233.2	95%		Inquiry
ADC-L-M0322	Azido-PEG4-CH2CO2H	201467-81-4		277.3	95%		Inquiry
ADC-L-M0323	Azido-PEG5-CH2CO2H	217180-81-9		321.3	95%		Inquiry
ADC-L-M0324	Azido-PEG8-CH2CO2H	1343472-07-0		453.5	95%		Inquiry
ADC-L-M0330	Azido-PEG5-NHS ester	1433996-86-1		432.4	95%		Inquiry
ADC-L-M0331	Azido-PEG6-NHS ester	2055014-64-5		476.5	95%		Inquiry