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Magic™ Antibody Discovery - Human Neuropilin-1 / NRP1 / CD304 (22-644) Membrane Protein, Partial, -His tag (CAT#: MP0712F)

This membrane protein is Human Neuropilin-1 / NRP1 / CD304 (22-644). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Neuropilin-1 / NRP1 / CD304
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 70.8 kDa. The protein migrates as 75-116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Phe 22 - Lys 644 (Accession # AAH07533).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >92% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Neuropilin-1 / NRP1 / CD304
  • Full Name
  • neuropilin 1
  • Introduction
  • This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
  • Alternative Names
  • NP1; NRP; BDCA4; CD304; VEGF165R; neuropilin-1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor

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