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Magic™ Membrane Protein Human PLXNC1 (Plexin C1) Expressed in NS0 for Antibody Discovery, Partial (35-944aa) (CAT#: MPX0295K)

Datasheet
This product is a 100.9 kDa Human PLXNC1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PLXNC1
  • Protein Length
  • Partial (35-944aa)
  • Protein Class
  • Receptor
  • Molecular Weight
  • 100.9 kDa
  • TMD
  • 1
  • Sequence
  • ADEPVWRSEQAIGAIA
    ASQEDGVFVASGSCLDQLDYSLEHSLSRLYRDQAGNCTEPVSLAPPARPR
    PGSSFSKLLLPYREGAAGLGGLLLTGWTFDRGACEVRPLGNLSRNSLRNG
    TEVVSCHPQGSTAGVVYRAGRNNRWYLAVAATYVLPEPETASRCNPAASD
    HDTAIALKDTEGRSLATQELGRLKLCEGAGSLHFVDAFLWNGSIYFPYYP
    YNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLV
    EALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFKTA
    ESHCKEGDQPERVQPIASSTLIHSDLTSVYGTVVMNRTVLFLGTGDGQLL
    KVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRI
    RVANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDIS
    SGAKKCPKIQIIRSSKEKTTVTMVGSFSPRHSKCMVKNVDSSRELCQNKS
    QPNRTCTCSIPTRATYKDVSVVNVMFSFGSWNLSDRFNFTNCSSLKECPA
    CVETGCAWCKSARRCIHPFTACDPSDYERNQEQCPVAVEKTSGGGRPKEN
    KGNRTNQALQVFYIKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGT
    STCDKDVIQVSHVLNDTHMKFSLPSSRKEMKDVCIQFDGGNCSSVGSLSY
    IALPHCSLIFPATTWISGGQNITMMGRNFDVIDNLIISHELKGNINVSEY
    CVATYCGFLAPSLKSSKVRTNVTVKLRVQDTYLDCGTLQYREDPRFTGYR
    VESEVDTELEVKIQKENDNFNISKKDIEITLFHGENGQLNCSFENITRNQ
    DLTTILCKIKGIKTASTIANSSKKVRVKLGNLELYVEQESVPST

Product Description

  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • PLXNC1
  • Full Name
  • Plexin C1
  • Introduction
  • This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene.
  • Alternative Names
  • PLXNC1; CD232; VESPR; PLXN-C1; plexin-C1; plexin (semaphorin receptor); receptor for viral semaphorin protein; receptor for virally-encoded semaphorin; virus-encoded semaphorin protein receptor; Plexin C1

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