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eldelumab (TAB-742)

DESCRIPTION CATALOG # SIZE PRICE
Anti-CXCL10 Therapeutic Antibody TAB-742 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant human monoclonal antibody expressed in CHO binding to human CXCL10. Eldelumab is a monoclonal antibody designed for the treatment of Crohn's disease and ulcerative colitis.
  • Target
  • C-X-C motif chemokine 10
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, IHC and most other immunological methods.
  • CAS
  • 946414-98-8
  • Predicted N terminal
  • QMQLVESG
  • Molecular Weight
  • 146.5 kDa
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

BACKGROUND

  • Introduction
  • Eldelumab is a monoclonal antibody designed for the treatment of Crohn's disease and ulcerative colitis.
  • Antigen Description
  • This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression.
  • Function
  • cAMP-dependent protein kinase regulator activity; chemokine activity; receptor binding;
  • Synonyms
  • CXCL10; chemokine (C-X-C motif) ligand 10; INP10, SCYB10, small inducible cytokine subfamily B (Cys X Cys), member 10; C-X-C motif chemokine 10; C7; crg 2; gIP 10; IFI10; IP 10; mob 1; gamma IP10; gamma-IP10; small-inducible cytokine B10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; protein 10 from interferon (gamma)-induced cell line; small inducible cytokine subfamily B (Cys-X-Cys), member 10; INP10; IP-10; crg-2; mob-1; SCYB10; gIP-10;

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