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Vapaliximab (TAB-261)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human AOC3 Therapeutic Antibody TAB-261 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to AOC3. Vapaliximab is a chimeric monoclonal antibody and an immunosuppressive drug.
  • Target
  • AOC3
  • Type
  • IgG2
  • Immunogen
  • Purified vessels from human peripheral lymph nodes.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • CAS
  • 336801-86-6
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G2, anti-(human vascular adhesion protein VAP-1) (human-mouse monoclonal 2D10 γ 2-chain), disulfide with human-mouse monoclonal2D10 Kappa?chain, dimer
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The product is a major protein on the adipocyte plasma membrane. It has adhesive properties and also has functional monoamine oxidase activity. A pseudogene for this gene has been discribed and is located approximately 9-kb downstream.
  • Function
  • aliphatic-amine oxidase activity; aminoacetone:oxygen oxidoreductase(deaminating) activity; calcium ion binding; cation channel activity; copper ion binding; copper ion binding; oxidoreductase activity; phenethylamine:oxygen oxidoreductase (deaminating) a
  • Synonyms
  • AOC3; amine oxidase, copper containing 3 (vascular adhesion protein 1); membrane primary amine oxidase; HPAO; VAP 1; VAP1; copper amine oxidase; vascular adhesion protein 1; semicarbazide-sensitive amine oxidase; SSAO; VAP-1;

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