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Rituximab (TAB-016)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD20 Therapeutic Antibody (rituximab) TAB-016 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to Human CD20. Rituximab (trade names rituximab and rituximab) is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells (this should not be confused with pancreatic β- or beta cells). Rituximab destroys B cells and is therefore used to treat diseases which are characterized by excessive numbers of B cells, overactive B cells, or dysfunctional B cells. This includes many lymphomas, leukemias, transplant rejection, and autoimmune disorders.
  • Target
  • CD20
  • Type
  • IgG1 - kappa
  • Immunogen
  • Human lymphoblastoid cell line SB
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, ELISA, IF, IP, FuncS, FC, WB and most other immunological methods.
  • CAS
  • 174722-31-7
  • Trade name
  • rituximab
  • Specificity
  • Tested positive against native human antigen
  • Protein Construction
  • Immunoglobulin G1,anti-(human CD20 (antigen)) (human-mouse monoclonal C2B8 gamma 1-chain), disulfide with human-mouse monoclonal C2B8 kappa-chain, dimer
  • Predicted N terminal
  • H Chain: QVQLQQPL Chain: QIVLSQS
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • CD20 is B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells.
  • Function
  • epidermal growth factor receptor binding;
  • Synonyms
  • MS4A1; membrane-spanning 4-domains, subfamily A, member 1; CD20; B-lymphocyte antigen CD20; B1; Bp35; MS4A2; CD20 antigen; CD20 receptor; leukocyte surface antigen Leu-16; B-lymphocyte cell-surface antigen B1; S7; CVID5; LEU-16; MGC3969;

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