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gemtuzumab ozogamicin (TAB-H37)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD33 Therapeutic Antibody TAB-H37 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) antibody to Human CD33. Gemtuzumab ozogamicin is a drug-linked monoclonal antibody (an antibody-drug conjugate) that was used to treat acute myelogenous leukemia. Gemtuzumab is a monoclonal antibody to CD33 linked to a cytotoxic agent from the class of calicheamicins.
  • Type
  • IgG
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, IHC and most other immunological methods.
  • CAS
  • 220578-59-6
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.

BACKGROUND

  • Antigen Description
  • CD33 or Siglec-3 is a transmembrane receptor expressed on cells of myeloid lineage. It is usually considered myeloid-specific, but it can also be found on some lymphoid cells. It binds sialic acids, therefore is a member of the SIGLEC family of lectins.
  • Function
  • receptor activity; sugar binding;
  • Synonyms
  • CD33; CD33 molecule; CD33 antigen (gp67); myeloid cell surface antigen CD33; FLJ00391; p67; sialic acid binding Ig like lectin 3; SIGLEC 3; SIGLEC3; gp67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC-3;

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