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pasotuxizumab (TAB-H54)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD3E Therapeutic Antibody TAB-H54 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized antibody to Human CD3E
  • Type
  • (scFv - heavy - kappa) - (scFv - heavy - lambda)
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, WB and most other immunological methods.
  • CAS
  • 1442657-12-6
  • Specificity
  • CD3E (CD3 epsilon) [Homo sapiens] ;
  • Protein Construction
  • Bispecific single chain antibodyscFv anti-FOLH1 (1-243) [humanized VH (Homo sapiens IGHV3- 11*01 (85.70%) – (IGHD )- IGHJ4*01) [8.8.14](1-121) – 15 – mer tris(tetraglycyl-seryl) linker (122-136) – humanized V-KAPPA (Homo sapiens IGKV1-16*01 (81.10%) – IGKJ2*01Q120>G (236)) [6.3.9](137-243)] -6-mer seryl-tetraglycyl-seryl linker (244-249) – scFv anti-CD3E (250-498) [Mus musculus VH (Mus musculus IGHV10-1*02 (91.90%) – (IGHD) – IGHJ3*01) [8.10.16] (250-374) -15-mertris(tetraglycyl-seryl) linker (375-389) – humanized V-LAMBDA (Homo sapiens IGLV7-43*01(85.10%)-IGLJ3*02 [9.3.9] (390-498)] – hexahistidine(499-504)
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

BACKGROUND

  • Antigen Description
  • CD3e molecule, epsilon also known as CD3E is a polypeptide which in humans is encoded by the CD3E gene which resides on chromosome 11.
  • Function
  • SH3 domain binding; T cell receptor binding; protein heterodimerization activity; protein kinase binding; receptor activity; receptor signaling complex scaffold activity; receptor signaling protein activity; transmembrane signaling receptor activity;
  • Synonyms
  • CD3E; CD3e molecule, epsilon (CD3-TCR complex); CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell antigen receptor complex, epsilon subunit of T3; T3E; TCRE; FLJ18683;

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