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vorsetuzumab (TAB-H76)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human CD70 Therapeutic Antibody TAB-H76 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) antibody to Human CD70. Vorsetuzumab is a monoclonal antibody designed for the treatment of cancer.
  • Type
  • IgG1 - kappa
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
  • CAS
  • 1165740-62-4
  • Specificity
  • CD70 (tumor necrosis factor superfamily member 7, TNFSF7, CD27LG, CD27L) [Homo sapiens]
  • Protein Construction
  • gamma1 heavy chain (1-448) [humanized VH (Homo sapiens IGHV1- 2*02 (86.70%) – (IGHD) – IGHJ6*01) [8.8.11] (1-118) – Homo sapiensIGHG1*01 (119-448)], (221-218') – disulfide withkappa light chain (1'-218') [humanized V- KAPPA (Homo sapiens IGKV4- 1*01 (79.20%) – IGKJ1*01) [10.3.9] (1'-111') – Homo sapiens IGKC*01(112'-218')]; (227-227":230-230") – bisdisulfide dimer
  • Purity
  • Purity >95% by SDS-PAGE.

BACKGROUND

  • Antigen Description
  • CD70 (Cluster of Differentiation 70) is a ligand for CD27.
  • Function
  • cytokine activity; protease binding; protein binding; receptor binding; tumor necrosis factor receptor binding;
  • Synonyms
  • CD70; CD70 molecule; CD27LG, TNFSF7, tumor necrosis factor (ligand) superfamily, member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7; CD27LG; TNFSF7;

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