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Biciromab (TAB-036-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Fibrin II, beta chain therapeutic Antibody Fab Fragment (FibriScint) TAB-036-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant antibody fragment Fab to Fibrin Ⅱ. Indium (111In) biciromab (INN, trade name FibriScint) was a drug targeting fibrin, a protein involved in the clotting of blood. It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism.
  • Target
  • Fibrin II, beta chain
  • Type
  • Fab' - G1 - kappa
  • Immunogen
  • NH2-terminal CNBr fragment of human fibrin II
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IP, IF, FuncS, FC, Neut, ELISA, IHC and most other immunological methods.
  • CAS
  • 138783-13-8
  • Trade name
  • fibriscint
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G (mouse monclonal T2G1Fab fragment anti-human fibrin II beta-chain), disulfide with mouse monoclonal T2G1 light chain
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

BACKGROUND

  • Introduction
  • Fab` fragment of a mouse monoclonal antibody directed to fibrinⅡ, beta chain, for the diagnosis of thromboembolismtargeting.
  • Antigen Description
  • Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed from fibrinogen by the protease thrombin, and is then polymerised to form a "mesh" that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site.Fibrin is involved in signal transduction, blood coagulation, and platelet activation.
  • Keywords
  • fibrinogen; Fibrin; Fibrin beta

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