Benralizumab

Cat

TAB-222

Product Overview

Recombinant monoclonal antibody to IL5RA. Benralizumab (INN) is a monoclonal antibody for the treatment of asthma. It is directed against the alpha-chain of the interleukin-5 receptor (CD125).

Target

IL5RA

Type

IgG1 - kappa

Immunogen

The details of the immunogen for this antibody are not available.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in WB, FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.

CAS

1044511-01-4

Specificity

Tested positive against native human antigen.

Protein Construction

Immunoglobulin G1, anti-(human interleukin 5 receptor alpha-chain) (human-mouse monoclonal MEDI-563 heavy chain), disulfide with human-mouse monoclonal MEDI-563 kappa-chain, dimer

Predicted N terminal

H chain: EVQLVQS; L chain: DIQMTQS

Molecular Weight

146054

Purity

>95.0% as determined by analysis by RP-HPLC.

Size

1mg

Storage

Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Antigen Description

This is the receptor for interleukin-5. The alpha chain binds to IL5.

Function

interleukin-5 receptor activity; protein binding; receptor activity;

Gene ID

3568

Synonyms

IL5RA; interleukin 5 receptor, alpha; IL5R; interleukin-5 receptor subunit alpha; CD125; CDw125; CD125 antigen; IL-5R subunit alpha; IL-5 receptor subunit alpha; interleukin 5 receptor type 3; interleukin-5 receptor alpha chain; HSIL5R3; MGC26560;

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