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Benralizumab (TAB-222)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IL5RA Therapeutic Antibody TAB-222 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to IL5RA. Benralizumab (INN) is a monoclonal antibody for the treatment of asthma. It is directed against the alpha-chain of the interleukin-5 receptor (CD125).
  • Target
  • IL5RA
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in WB, FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • CAS
  • 1044511-01-4
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1, anti-(human interleukin 5 receptor alpha-chain) (human-mouse monoclonal MEDI-563 heavy chain), disulfide with human-mouse monoclonal MEDI-563 kappa-chain, dimer
  • Predicted N terminal
  • H chain: EVQLVQS; L chain: DIQMTQS
  • Molecular Weight
  • 146054
  • Purity
  • >95.0% as determined by analysis by RP-HPLC.
  • Size
  • 1mg
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • This is the receptor for interleukin-5. The alpha chain binds to IL5.
  • Function
  • interleukin-5 receptor activity; protein binding; receptor activity;
  • Synonyms
  • IL5RA; interleukin 5 receptor, alpha; IL5R; interleukin-5 receptor subunit alpha; CD125; CDw125; CD125 antigen; IL-5R subunit alpha; IL-5 receptor subunit alpha; interleukin 5 receptor type 3; interleukin-5 receptor alpha chain; HSIL5R3; MGC26560;

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