Onartuzumab
DESCRIPTION |
CATALOG # |
SIZE |
PRICE |
Anti-Human Met(c-Met) therapeutic Antibody Fab Fragment |
TAB-190-F(P) |
1mg |
Please Inquiry |
Product Detail
- Cat
- TAB-190-F(P)
- Product Overview
- Recombinant monoclonal antibody Fragment Fab to Met. Onartuzumab is a humanized monoclonal antibody designed for the treatment of cancer.
- Target
- Met(c-Met)
- Type
- Fab / Fc - G1 - kappa
- Immunogen
- The details of the immunogen for this antibody are not available.
- Species Reactivity
- Human
- Expression Host
- E. coli
- Applications
- Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
- CAS
- 1133766-06-9
- Specificity
- Tested positive against native human antigen.
- Protein Construction
- Immunoglobulin G1, anti-(human scatter factor receptor kinase)(human-mouse monoclonal MetMAb heavy chain), disulfide with human-mouse monoclonal MetMAb kappa-chain, disulfide with human-mouse monoclonal MetMAb heavy chain hinge region-CH2-CH3 domain-containing fragment
- Predicted N terminal
- H chain: EVQLVES; L chain: DIQMTQS
- Molecular Weight
- 99146
- Purity
- >95.0% as determined by analysis by RP-HPLC.
- Size
- 1mg
- Storage
- At -20°C for one year.
Background
- Antigen Description
- Receptor for hepatocyte growth factor and scatter factor. Has a tyrosine-protein kinase activity. Functions in cell proliferation, scattering, morphogenesis and survival.
- Function
- ATP binding; hepatocyte growth factor-activated receptor activity; nucleotide binding; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity; receptor activity;
- Gene ID
- 4233
- Synonyms
- MET; met proto-oncogene (hepatocyte growth factor receptor); hepatocyte growth factor receptor; HGFR; RCCP2; SF receptor; HGF receptor; oncogene MET; HGF/SF receptor; proto-oncogene c-Met; scatter factor receptor; tyrosine-protein kinase Met; met proto-oncogene tyrosine kinase; AUTS9; c-Met;
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