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Tenatumomab (TAB-877)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human Tenascin C/TNC Therapeutic Antibody TAB-877 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant humanized (from mouse) antibody expressed in CHO binding to human Tenascin C/TNC. Tenatumomab is a monoclonal antibody designed for the treatment of cancer.
  • Target
  • Tenascin C/TNC
  • Type
  • IgG2b
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF, ICC and most other immunological methods.
  • Predicted N terminal
  • EIQLQQSG
  • Molecular Weight
  • Approximately 150 kDa
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Introduction
  • Tenatumomab is a monoclonal antibody designed for the treatment of cancer.
  • Antigen Description
  • Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
  • Function
  • binding; receptor binding; syndecan binding;
  • Synonyms
  • TNC; tenascin C; hexabrachion (tenascin C, cytotactin) , HXB; tenascin; hexabrachion (tenascin); MGC167029; TN; GP 150-225; cytotactin; neuronectin; myotendinous antigen; tenascin-C isoform 14/AD1/16; glioma-associated-extracellular matrix antigen; GP; JI; HXB; GMEM; TN-C; 150-225;

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