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Alacizumab pegol (TAB-202)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human VEGF Receptor 2 Therapeutic Antibody, F(ab')2 fragment TAB-202 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant antibody fragment Fab to VEGF Receptor 2. Alacizumab pegol is an antineoplastic agent. Chemically, it is a pegylated F(ab')2 fragment of a monoclonal antibody.
  • Target
  • VEGF Receptor 2
  • Type
  • di - Fab'
  • Immunogen
  • Recombinant human soluble extracellular KDR (110 kDa) native protein.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
  • CAS
  • 934216-54-3
  • Specificity
  • Tested positive against native human antigen.
  • Predicted N terminal
  • H chain: EVQLVES; L chain: DIQMTQS
  • Purity
  • Purity >95% by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi"s sarcoma lesions.
  • Function
  • ATP binding; Hsp90 protein binding; growth factor binding; integrin binding; nucleotide binding; protein binding; protein tyrosine kinase activity; receptor activity; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyro
  • Synonyms
  • KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR; VEGFR2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor;

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