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Radretumab (TAB-193)

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human fibronectin extra domain-B Therapeutic Antibody TAB-193 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to fibronectin extra domain-B. Radretumab is an antineoplastic. It binds to fibronectin extra domain-B.
  • Target
  • fibronectin extra domain-B
  • Type
  • [(scFv - heavy - kappa) - IGHE - CH4]2
  • Immunogen
  • A region in the ED-A domain of human cellular fibronectin.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.
  • CAS
  • 1253180-81-2
  • Specificity
  • Tested positive against native human antigen.
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans.
  • Function
  • collagen binding; extracellular matrix structural constituent; heparin binding; protein binding;
  • Synonyms
  • FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;

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