Radretumab

Cat

TAB-193

Product Overview

Recombinant monoclonal antibody to fibronectin extra domain-B. Radretumab is an antineoplastic. It binds to fibronectin extra domain-B.

Target

fibronectin extra domain-B

Type

[(scFv - heavy - kappa) - IGHE - CH4]2

Immunogen

A region in the ED-A domain of human cellular fibronectin.

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in ELISA, IP, FC, FuncS, Neut, IF, ICC and most other immunological methods.

CAS

1253180-81-2

Specificity

Tested positive against native human antigen.

Purity

>95.0% as determined by analysis by SDS-PAGE.

Size

1mg

Storage

Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

Antigen Description

Fibronectin is a high-molecular weight (~440kDa) glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans.

Function

collagen binding; extracellular matrix structural constituent; heparin binding; protein binding;

Gene ID

2335

Synonyms

FN1; fibronectin 1; fibronectin; CIG; cold insoluble globulin; FINC; GFND2; LETS; migration stimulating factor; MSF; cold-insoluble globulin; migration-stimulating factor; FN; FNZ; ED-B; GFND; DKFZp686H0342; DKFZp686I1370; DKFZp686F10164; DKFZp686O13149;

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