Anti-IL2RA Antibody Fab (MOM-18155-F(P))
|Recombinant Anti-Human IL2RA Antibody Fab Fragment
- Product Overview
- Recombinant Mouse Antibody Fab Fragment binds selectively to Human CD25, expressed in E. coli
- Fab Fragment based on Mouse IgG1 - kappa
- Human leucocytes.
- Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
- Specific Activity
- Tested positive against native antigen.
- Predicted N terminal
- H chain: QVQLVQS; L Chain: EIVLTQS
- >95.0% as determined by analysis by RP-HPLC.
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
- Antigen Description
- Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10 (IDDM10) [MIM:601942]. A multifactorial disorder of glucose homeostasis that is characterized by susceptibility to ketoacidosis in the absence of insulin therapy. Clinical fetaures are polydipsia, polyphagia and polyuria which result from hyperglycemia-induced osmotic diuresis and secondary thirst. These derangements result in long-term complications that affect the eyes, kidneys, nerves, and blood vessels.
- drug binding; interleukin-2 binding; interleukin-2 receptor activity; receptor activity;
- IL2RA; interleukin 2 receptor, alpha; IL2R; interleukin-2 receptor subunit alpha; CD25; p55; IL2-RA; IL-2-RA; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha; TCGFR; IDDM10;
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