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Anti-TAG-72 Antibody Fab (MOM-18002-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TAG-72 Antibody Fab Fragment MOM-18002-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment binds selectively to Human TAG72, expressed in Chinese Hamster Ovary (CHO cell)
  • Target
  • TAG72
  • Type
  • Fab Fragment based on Mouse IgG1
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Introduction
  • This monoclonal antibody can be attached to the chelator pentetic acid (DTPA) linked to the tripeptide glycine (G) – L-tyrosine (Y) – L-lysine (K), which chelates Indium 111 and binds selectively to cell-surface TAG-72 expressed on colorectal tumors. This product has the same active ingredient as Satumomab Pendetide.
  • Antigen Description
  • The majority of human adenocarcinomas including colorectal, pancreatic, gastric, ovarian, endometrial, mammary, and non-small cell lung cancer display some cell populations that are positive for TAG72. About 60% of carcinoma patients express TAG72 in their sera. TAG72 is reportedly useful in distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
  • Keywords
  • CA 72.4; TAG 72; Tumor associated Glycoprotein 72; OncoScint CR103; Satumomab Pendetide

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