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Anti-TNF Antibody (MOM-18138)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human TNF Antibody MOM-18138 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized Antibody is against Human TNF-alpha, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • TNF-alpha
  • Type
  • Humanized VH - VH' - VH
  • Immunogen
  • Full length native protein (purified) (Human).
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Protein Construction
  • Immunoglobulin single chain VH-VH"-VH, trivalent bispecific anti-[Homo sapiens TNF (tumor necrosis factor, TNF superfamily member 2, TNFSF2, TNFA, TNF-alpha)] VH and anti-[Homo sapiens ALB (albumin, human serum albumin, HSA)] VH", humanized Lama glama mon
  • Predicted N terminal
  • H chain: EVQLVES
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
  • Function
  • cytokine activity; identical protein binding; protease binding; protein binding; transcription regulatory region DNA binding; tumor necrosis factor receptor binding;
  • Synonyms
  • TNF; tumor necrosis factor; TNFA, tumor necrosis factor (TNF superfamily, member 2); DIF; TNF superfamily; member 2; TNF alpha; TNFSF2; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; TNF superfamily, member 2; tumor necrosis factor alpha; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2; TNFA; TNF-alpha;

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