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Recombinant Mouse Antibody is against Human CCL21, expressed in Chinese Hamster Ovary cells(CHO)
Suitable for use in IF, IP, Neut and most other immunological methods.
Tested positive against native antigen.
Purity >95% by SDS-PAGE.
At -20°C for one year.
Human CCL21 is a beta or C-C chemokine identified in the Expressed Sequence tagged (EST) database by three independent groups. CCL21 contains four conserved cysteine (C) residues which are characteristic of beta-chemokines. Human CCL21 cDNA encodes a 134 amino acid precursor protein, a 23 amino acid signal peptide and a 111 amino acid mature protein. Unlike other C-C chemokines, CCL21 is not chemotactic for monocytes and neutrophils. A growing body of work suggests that CCL21 influences lymphocyte homing to secondary lymphoid organs, integrin-mediated lymphocyte adhesion, and may act via the EBI1 ligand chemokine (ELC) receptor, CCR7.