Anti-cd18 Antibody

Cat

MOM-18154

Product Overview

Recombinant Humanized (from mouse) Antibody binds selectively to Human CD18, expressed in Chinese Hamster Ovary cells(CHO)

Target

CD18

Type

Humanized (from mouse) IgG1

Immunogen

Tissue / cell preparation (Human). (Leucocytes of a patient suffering from a LGL-type leukaemia).

Species Reactivity

Human

Expression Host

CHO

Applications

Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.

Specificity

Tested positive against native antigen.

Purity

>95.0% as determined by analysis by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Antigen Description

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Function

glycoprotein binding; protein kinase binding; receptor activity; receptor binding

Gene ID

3689

Synonyms

ITGB2; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; integrin beta-2; integrin beta chain, beta 2; complement receptor C3 beta-subunit; complement receptor C3 subunit beta; leukocyte cell adhesion molecule CD18; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; cell surface adhesion glycoprotein LFA-1/CR3/P150,959 beta subunit precursor); integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit); CD18 antigen

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