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Anti-cxcr5 Antibody Fab (MOM-18338-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human cxcr5 Antibody Fab Fragment MOM-18338-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is directed against Human CXCR5, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • CXCR5
  • Type
  • Fab
  • Immunogen
  • Recombinant full length Human CXCR5 protein
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95%, by SDS-PAGE with silver staining, under reducing conditions.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • The CXCR5 gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. CXCR5 protein is predicted to be a seven transmembrane G protein coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of the gene and its mouse conterpart strongly suggest the essential function of the protein is in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen.
  • Function
  • C-X-C chemokine receptor activity; G-protein coupled receptor activity; receptor activity; signal transducer activity;
  • Synonyms
  • CXCR5; chemokine (C-X-C motif) receptor 5; BLR1, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C X C motif) receptor 5) , Burkitt lymphoma receptor 1, GTP binding protein; C-X-C chemokine receptor type 5; CD185; MDR15; CXC-R5; CXCR-5; MDR-15; monocyte-derived receptor 15; Burkitt lymphoma receptor 1, GTP-binding protein; Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5); BLR1; MGC117347

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