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Anti-epha2 Antibody scFv (MOM-18552-S(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human epha2 Antibody scFv Fragment MOM-18552-S(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody scFv Fragment is bind to Human EPHA2, expressed in E. coli
  • Target
  • EPHA2
  • Type
  • scFv
  • Immunogen
  • Recombinant mouse EphA2 extracellular domain
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in ELISA, WB, Neut and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • >95%, by SDS-PAGE with silver staining, under reducing conditions.
  • Storage
  • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

BACKGROUND

  • Antigen Description
  • Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 and -A5. Plays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). Induces apoptosis in a p53/TP53-independent, caspase-8-dependent manner.
  • Function
  • ATP binding; ephrin receptor activity; nucleotide binding; protein binding; receptor activity; transmembrane receptor protein tyrosine kinase activity;
  • Synonyms
  • EPHA2; EPH receptor A2; ECK, EphA2; ephrin type-A receptor 2; soluble EPHA2 variant 1; tyrosine-protein kinase receptor ECK; epithelial cell receptor protein tyrosine kinase; ECK; CTPA; ARCC2; CTPP1;

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