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Anti-epor Antibody Fab (MOM-18355-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human epor Antibody Fab Fragment MOM-18355-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is directed against Human EPOR, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • EPOR
  • Type
  • Fab
  • Immunogen
  • Human recombinant EPO Receptor (extracellular domain)
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
  • Function
  • erythropoietin receptor activity; identical protein binding; protein binding; receptor activity;
  • Synonyms
  • EPOR; erythropoietin receptor; EPO-R; MGC138358

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