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Anti-tlr3 Antibody (MOM-18621)

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human tlr3 Antibody MOM-18621 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody is specific to Human TLR3, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • TLR3
  • Type
  • IgG
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
  • Specificity
  • Tested positive against native antigen.
  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
  • Function
  • double-stranded RNA binding; double-stranded RNA binding; receptor activity; transmembrane signaling receptor activity;
  • Synonyms
  • TLR3; toll-like receptor 3; CD283; IIAE2;

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