Recombinant Anti-CLDN3 Mab

Cat

HOM-19260

Product Overview

Recombinant humanized antibody expressed in CHO binding to human CLDN3.

Target

CLDN3

Type

Human IgG

Species Reactivity

Human

Expression Host

CHO

Applications

ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.

Clone

Monoclonal

Molecular Weight

145.41 kDa

Purity

>95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.

Storage

Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.

Stability

Samples are stable for up to twelve months from date of receipt at - °C and are stable for six months at 4 °C.

Ship

2-8°C, BLUE ICE

Antigen Description

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Function

identical protein binding; structural molecule activity; transmembrane signaling receptor activity;

Gene ID

1365

Synonyms

CLDN3; claudin 3; C7orf1, CPETR2; claudin-3; Clostridium perfringens enterotoxin receptor 2; CPE R2; CPE receptor 2; HRVP1; RVP1; ventral prostate.1 like protein; CPE-R 2; CPE-receptor 2; ventral prostate.1-like protein; ventral prostate.1 protein homolog; C7orf1; CPE-R2; CPETR2;

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