Creative Biolabs has comprehensive development capability to offer various stable cell line services. With our elegant gene screening and amplification system, custom stable cell line can be generated either based on gene provided by our clients or synthesized by our relevant services.
The laboratory technique of maintaining live cell lines separated from their original tissue source has become robust but also crucial laboratory tools. It is important to generate stable cell lines in most aspects of biomedical research and development. Stable cell lines are immortal cells which are able to express interested protein (or other useful molecules) stably under controlled level. In general, the developed stable cell lines are expected to grow continuously over a prolonged period and have no considerable change for the expression level of target gene. To make a truly overexpression stable cell line, the interested gene is usually put under the control of a strong promoter and then integrated into host chromosomes to retain intact host genetic materials in continuous cell culture.
Currently, stable cell lines have been widely used in various research applications. As one of the best solutions in protein manufacturing, stable cell lines have been utilized for various different aims, including the production of therapeutic or experimental protein (e.g. recombinant antibody), screening of experimental drugs, functional study of gene, assay development and so on. Especially for clinical use, produce target molecules with a qualified stable cell line can contribute to an increased acceptability and reliability. However, the development and production of a qualified stable cell line is a complex and time-consuming challenge, which requiring extensive experience and technique. Creative Biolabs is just able to relieve our customers from this tedious work by our relevant services.
Creative Biolabs has extensive experience in the field of cell culture and cell line generation. Our scientists have developed several perfect stable cell lines and also produced a large number of antibodies and proteins through stable cell lines. Our specific biosimilar cell lines and hybridoma cell lines are available in-house, and we are also pleased to provide custom strains to meet our clients’ individual requirement.