ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-208	APN-C3-PEG4-alkyne	2183440-36-8		469.5	95%		Inquiry
ADC-L-209	Propargyl-PEG2-acrylate	52436-42-7		154.2	95%		Inquiry
ADC-L-210	bis-PEG2-endo-BCN	1476737-97-9		500.6	95%		Inquiry
ADC-L-211	Gly-PEG3-endo-BCN, TFA salt	2354291-37-3		453.6	95%		Inquiry
ADC-L-212	Boc-Gly-PEG3-endo-BCN	2110444-63-6		553.7	95%		Inquiry
ADC-L-213	Aminoethyl-SS-ethylalcohol	15579-01-8		153.3	95%		Inquiry
ADC-L-214	Aminoethyl-SS-propionic acid	15579-00-7		181.3	95%		Inquiry
ADC-L-215	Amino-SS-PEG12-acid			709.9	95%		Inquiry
ADC-L-216	Aminoethyl-SS-ethylamine	51-85-4		152.3	95%		Inquiry
ADC-L-218	NHS-PEG4-SS-PEG4-NHS			899.0	95%		Inquiry
ADC-L-219	t-Boc-Cystamine	485800-26-8		252.4	95%		Inquiry
ADC-L-220	Amino-ethyl-SS-PEG3-NHBoc	2144777-87-5		384.6	95%		Inquiry
ADC-L-221	Azidoethyl-SS-propionic acid	2228857-32-5		207.3	95%		Inquiry
ADC-L-222	Azido-SS-PEG2-acid	2144777-72-8		295.4	95%		Inquiry
ADC-L-223	Azidoethyl-SS-propionic NHS ester	2243566-44-9		304.3	95%		Inquiry
ADC-L-224	Azidoethyl-SS-ethylalcohol	1807540-82-4		179.3	95%		Inquiry
ADC-L-225	Azidoethyl-SS-ethylamine	1807512-40-8		178.3	95%		Inquiry
ADC-L-226	N3-SS-N3	352305-38-5		204.3	95%		Inquiry
ADC-L-227	Azido-PEG3-SS-PEG3-azide	1310827-27-0		468.6	95%		Inquiry
ADC-L-228	Azidoethyl-PEG2-t-Butyl ester	2144777-83-1		351.5	95%		Inquiry