Safety Evaluation Service for Skincare Exosome

Overview Services Features FAQs

Overview

Safety Issues of Skincare Exosome Product before Entering the Trial Stage

Stem cell-derived exosomes are rich in growth factors and cytokines and are easily internalized by skin cells. Multiple studies have shown that these beneficial actives enter skin cells to promote skin cell regeneration, repair damaged tissue, and resist oxidative damage, resulting in improved skin texture and smoothness. It should be pointed out that although exosome products have many advantages in the field of skincare, their safety and effectiveness still need further research and evaluation. Creative Biolabs has launched the safety evaluation service for skincare exosome product to help customers grasp product quality.

Fig.1 Schematic representation showing skin regenerative abilities of exosomes.^1,2

Before skincare exosome enter the volunteer trial phase, the following safety issues need to be assessed.

Potential toxicity. Exosomes may contain components that are toxic to the human body, such as endotoxins, proteins, nucleic acids, etc. Relevant toxicology studies are required to determine their potential toxicity and safety.
Allergic reactions. Proteins, nucleic acids and other components contained in exosomes may cause allergic reactions, and relevant allergenicity tests are required to evaluate their allergies.
Infection risk. Exosomes produced by certain cell types may be infected by some pathogens or bacteria may be introduced during the production of exosomes. Therefore, pathogen detection and sterility testing of exosome samples are required before the test to ensure that there is no risk of infection.
Immune response. Although exosomes have almost no immunogenicity. However, in the actual application process, exosomes may still cause immune responses. Therefore, it is necessary to carry out relevant immunological research to evaluate its immunological risk.
Skin irritation. Exosomes may produce a certain degree of irritation, so relevant skin irritation tests need to be carried out to evaluate their irritation to the skin.

Services

The Safety Evaluation System for Skincare Exosome Product in Creative Biolabs

As a professional biotechnology company, Creative Biolabs can provide a full range of skincare exosome evaluation services, including but not limited to the following:

Safe exosome preparation: We provide skincare exosome preparation services under standard clean conditions according to customer needs.
Infection risk assessment: We provide standard sterility testing, endotoxin testing, mycoplasma testing, and virus testing to evaluate product safety from the most basic perspective.
Exosome components analysis: We use mass spectrometry to analyze the components in exosomes to determine their composition and content.
Exosome efficacy evaluation: We provide various types of skin cell models and animal models to evaluate the functions of exosomes such as anti-aging, promoting skin regeneration, moisturizing, and repairing.
Harmful ingredients evaluation: Skincare exosome products may contain some heavy metals, hormones, or other harmful substances. We provide standard harmful ingredient testing services to provide important parameters for product safety.
Exosome safety evaluation: We conduct relevant safety evaluations such as toxicology research, immunology research, allergenicity test, skin irritation test, etc., to ensure the safety of exosomes in human skincare.
Exosome storage evaluation: We provide the most recognized antiseptic efficacy verification service to evaluate the antiseptic effect accurately and comprehensively.

Features

Comprehensive, reliable, high-quality evaluation system
Effective models
Relevant skincare-grade exosome preparation services
Professional technical team and advanced equipment

If you need to evaluate the safety of skincare exosome product, please contact us.

FAQs

Q: How can your safety evaluation services benefit my skincare product development?

A: Our comprehensive safety evaluation services ensure that your skincare exosome products meet the highest safety and quality standards, helping you anticipate and mitigate the risk of adverse reactions.

Q: What sets your exosome safety evaluation apart from others?

A: We offer a unique combination of advanced testing methods, a highly experienced technical team, and personalized service plans tailored to your specific needs, ensuring a thorough and accurate evaluation process.

Q: What kind of turnaround time can we expect for the evaluation process?

A: While the exact timeframe depends on the specific tests and scope of the evaluation, we prioritize efficiency and will provide a detailed timeline at the start of the project to ensure timely delivery of results.

References

Yang, GH.; et al. Overcome the barriers of the skin: exosome therapy. Biomaterials Research. 2021, 25(1):22.
Distributed under Open Access license CC BY 4.0, without modification.