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Magic™ Antibody Discovery - Human PD-L2 / B7-DC Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1469F)

This membrane protein is Human PD-L2 / B7-DC (20-219). It has been tested in SDS-PGAE, SEC-HPLC, BLI, FACS, Cell-based assay. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PD-L2 / B7-DC
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 49.2 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Leu 20 - Pro 219 (Accession # AAI13679)

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PGAE, SEC-HPLC, BLI, FACS, Cell-based assay
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS (pH7.4). Trehalose is added as protectant before lyophilization.

    Please contact us for customized formulation or product form if needed.

Target

  • Target Protein
  • PD-L2 / B7-DC
  • Full Name
  • programmed cell death 1 ligand 2
  • Introduction
  • This gene is nvolved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (which is evaluated by similarity).
  • Alternative Names
  • B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; programmed cell death 1 ligand 2; B7 dendritic cell molecule; B7-DC; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2

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