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Magic™ Membrane Protein Human C5AR2 (Complement C5a receptor 2) Full Length (CAT#: MPC0043K) Made to Order

This product is a 36 kDa Human C5AR2 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • C5AR2
  • Protein Length
  • Full length
  • Protein Class
  • GPCR
  • Molecular Weight
  • 36 kDa
  • TMD
  • 7
  • Sequence
  • MGNDSVSYEYGDYSDLSDRPVDCLDGACLAIDPLRVAPLPLYAAIFLVGV
    PGNAMVAWVAGKVARRRVGATWLLHLAVADLLCCLSLPILAVPIARGGHW
    PYGAVGCRALPSIILLTMYASVLLLAALSADLCFLALGPAWWSTVQRACG
    VQVACGAAWTLALLLTVPSAIYRRLHQEHFPARLQCVVDYGGSSSTENAV
    TAIRFLFGFLGPLVAVASCHSALLCWAARRCRPLGTAIVVGFFVCWAPYH
    LLGLVLTVAAPNSALLARALRAEPLIVGLALAHSCLNPMLFLYFGRAQLR
    RSLPAACHWALRESQGQDESVDSKKSTSHDLVSEMEV

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • C5AR2
  • Full Name
  • Complement C5a receptor 2
  • Introduction
  • This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • C5L2; GPF77; GPR77; C5a anaphylatoxin chemotactic receptor 2; C5a anaphylatoxin chemotactic receptor C5L2; G protein-coupled receptor 77; G protein-coupled receptor C5L2; C5AR2; Complement C5a receptor 2

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