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Magic™ Membrane Protein Human PCDH12 (Protocadherin 12) Expressed in CHO for Antibody Discovery, Partial (25-705aa) (CAT#: MPX0325K)

This product is a 75 kDa Human PCDH12 membrane protein expressed in CHO. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PCDH12
  • Protein Length
  • Partial (25-705aa)
  • Protein Class
  • Cell adhesion
  • Molecular Weight
  • 75 kDa
  • TMD
  • 1
  • Sequence
  • QEVTTLTVKYQVSEEVPSGTVIGKLS
    QELGREERRRQAGAAFQVLQLPQALPIQVDSEEGLLSTGRRLDREQLCRQ
    WDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEISESASL
    RTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVK
    ELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLA
    LEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAK
    TGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIP
    SIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNGLVHCWLSQELGHF
    RLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQI
    SDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRIQ
    DSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVS
    VWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETPNGLGP
    AGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILN
    PHTGQLFVNVTNASSLIGSEWELEIVVEDQGSPPLQTRALLRVMFVTSVD
    HLRDS

Product Description

  • Expression Systems
  • CHO
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 250 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >90%, by SDS-PAGE with silver staining
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • PCDH12
  • Full Name
  • Protocadherin 12
  • Introduction
  • This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.
  • Alternative Names
  • PCDH12; DMJDS1; VECAD2; VE-cadherin-2; protocadherin-12; VE-cad-2; VE-cadherin 2; vascular cadherin-2; vascular endothelial cadherin 2; Protocadherin 12

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