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Magic™ Membrane Protein Human TMPO (Thymopoietin) Full Length (CAT#: MPC4058K) Made to Order

This product is a made-to-order Human TMPO membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TMPO
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 1
  • Sequence
  • MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNR
    PPLPAGTNSKGPPDFSSDEEREPTPVLGSGAAAAGRSRAAVGRKATKKTD
    KPRQEDKDDLDVTELTNEDLLDQLVKYGVNPGPIVGTTRKLYEKKLLKLR
    EQGTESRSSTPLPTISSSAENTRQNGSNDSDRYSDNEEDSKIELKLEKRE
    PLKGRAKTPVTLKQRRVEHNQSYSQAGITETEWTSGSSKGGPLQALTRES
    TRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTG
    NFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFP
    YEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADV
    KSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP
    RKSN

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • TMPO
  • Full Name
  • Thymopoietin
  • Introduction
  • Through alternative splicing, this gene encodes several distinct LEM domain containing protein isoforms. LEM domain proteins include inner nuclear membrane and intranuclear proteins, and are involved in a variety of cellular functions including gene expression, chromatin organization, and replication and cell cycle control. The encoded alpha isoform is broadly diffuse in the nucleus and contains a lamin binding domain, while the beta and gamma isoforms are localized to the nuclear membrane and contain an HDAC3 interaction domain. The distinct isoforms may compete with each other when acting to chaperone other proteins and regulate transcription.
  • Alternative Names
  • TMPO; TP; LAP2; CMD1T; LEMD4; PRO0868; LEM domain containing 4; lamina-associated polypeptide 2; Thymopoietin

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