Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsCreative Biolabs is a world-leading service provider for immunotherapy. We have one of the world’s largest collection of antagonistic antibodies targeting various biomarkers, and we continue to innovate the immunotherapy technology to achieve even greater results. Based on years of research, now we offer high-quality customer service covering the entire antagonistic antibody development process to promote the therapeutic of renal cell carcinoma.
RCC, which is also called hypernephroma, renal adenocarcinoma, or renal or kidney cancer, is not a single entity, but rather comprises a population of tumors that originate from the highly heterogeneous epithelium of renal tubules. Based on the Heidelberg classification of renal cell tumors, histologic subtypes of RCC can be classified into clear cell adenocarcinoma, chromophobe collecting duct carcinoma, papillary carcinoma, and unclassified carcinomas. As the most common kind of kidney cancer found in adults, RCC has the highest cancer-specific mortality rate with an annually increasing incidence. Chemotherapy and radiation are two of the principal modes of cancer treatment. However, the effectiveness of chemotherapy and radiation are limited by drug resistance. To date, effective treatment for RCC is still unavailable.
Fig.1 The programmed cell death 1 (PD-1)/PD-L1 pathway. (Santarpia, 2015)
Recently, antagonistic antibodies act as immune checkpoint inhibitors targeting numerous pathways have been developed for the treatment of cancer. It has been reported that inhibitors against the programmed death 1 (PD-1) tumor escape pathway are active against advanced RCC. Particularly, when PD-1 ligand 1 (PD-L1) expressed by tumors, it is often associated with tumor-infiltrating lymphocytes, which indicates an ongoing antitumor response with the potential to be modulated by anti-PD-1 pathway agents. In this condition, in tumor microenvironments where PD-L1 is constitutively expressed or inducible, strategies that inhibit the PD-1 pathway may be more successful at generating the antitumor effect. Working in the field of antibody discovery for years, we have successfully established advanced technology platforms to offer comprehensive antibody development and engineering services to develop specific antagonistic antibody for the treatment of RCC.
Creative Biolabs is dedicated to promoting the development of immunotherapy. Our experienced scientists are happy to help global customers find the most appropriate plan to best suit your technical, program and budget requirements which can greatly assist your research. If you are interested in the service we offer, please feel free to contact us for more detailed information.
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All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
