The yeast protein expression system is the most economical eukaryotic expression system for both secretion and intracellular expression. It is ideally suitable for large-scale production of recombinant eukaryotic proteins. Creative Biolabs provides yeast cells protein expression service which considers promoters, optimal copies of vector per cell, inducibility, signal peptides, and cellular location, which are essential for high-level recombinant protein production.
Our expertise in yeast protein expression spans both P. pastoris and S. cerevisiae expression systems. If you’re looking for protein production via a fed-batch Pichia process, we have the experienced and credentialed staff to move your project forward.
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Creative Biolabs's engineering-enhanced protein expression technologies enable a high success rate of over 95% over a wide variety of recombinant proteins, and our proprietary technology is pushing yields even higher. Many secretory proteins that bacterial expression systems yield as insoluble or inactive inclusion bodies can be produced successfully by our yeast expression system using native or yeast secretion signals. We boost recombinant protein production per cell by increasing the protein per mRNA ratio across a range of eukaryotic production hosts. We can increase the production yield of your recombinant protein and can be combined with transcription-enhancing or other production-improving technologies.
Creative Biolabs has identified DNA elements that are instrumental in increasing translation rates when included in recombinant protein expression vectors. Using a range of yeast and fungal cell types, the functionality of our technology has been confirmed for a variety of industry-relevant platforms. Depending on initial expression levels, expression of secreted recombinant proteins can be increased several-fold, and is coupled to a similar increase in recombinant protein to mRNA ratios. Please feel free to contact us for more information.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.