Ixekizumab
DESCRIPTION |
CATALOG # |
SIZE |
PRICE |
Anti-Human IL17RA Therapeutic Antibody |
TAB-217 |
1mg |
Please Inquiry |
Product Detail
- Cat
- TAB-217
- Product Overview
- Recombinant monoclonal antibody to IL17RA. Ixekizumab is a humanized monoclonal antibody used in the treatment of autoimmune diseases.
- Target
- IL17RA
- Type
- IgG4 - kappa
- Immunogen
- The details of the immunogen for this antibody are not available.
- Species Reactivity
- Human
- Expression Host
- CHO
- Applications
- Suitable for use in WB, IP, IF, FuncS, FC, Neut, ELISA and most other immunological methods.
- CAS
- 1143503-69-8
- Specificity
- Tested positive against native human antigen.
- Protein Construction
- Immunoglobulin G4, anti-(human interleukin 17A) (human monoclonal LY2439821 γ4-chain), disulfide with human monoclonal LY2439821 kappa-chain, dimer
- Predicted N terminal
- H chain: QVQLVQS; L chain: DIVMTQT
- Molecular Weight
- 146200
- Purity
- Purity >95% by SDS-PAGE.
- Size
- 1mg
- Storage
- Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
- Antigen Description
- Interleukin 17 Receptor Alpha is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis.
- Function
- interleukin-17 receptor activity; receptor activity;
- Gene ID
- 23765
- Synonyms
- IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262;
- Download Datasheet:
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