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Sulesomab (TAB-045-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Anti-Human NCA-90 Therapeutic Antibody Fab Fragment(LeukoScan) TAB-045-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody Fragment Fab to NCA-90. Technetium (99mTc) sulesomab (trade name LeukoScan) is a mouse monoclonal antibody labelled with technetium-99m, a radionuclide.
    It is approved for the imaging of infections and inflammations in patients with suspected osteomyelitis, and is being investigated for other purposes like the detection of soft tissue infections.
  • Target
  • NCA-90
  • Type
  • Fab' - G1
  • Immunogen
  • Partially purified carcinoembryonic antigen (CEA) derived from GW-39 human colon adenocarcinoma xenografts.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, IHC and most other immunological methods.
  • CAS
  • 167747-19-5
  • Trade name
  • leukoscan
  • Specificity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1,anti-(human NCA-90 granulocyte cell antigen) Fab" fragment (mouse monoclonalIMMU-MN3 g1-chain), disulfide with mousemonoclonal IMMU-MN3 light chain
  • Predicted N terminal
  • H chain: QVQLQES; L chain: SIVMTQT
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • One of the nonspecific cross-reacting antigens found to be expressed on a variety of cell types. In the nomenclature of CD antigens this protein has been given the designation CD66a. NCA-90 and NCA-50 have the same sequence and the same placement of glycosylation sites despite their differences in molecular masses.
  • Function
  • protein binding;
  • Synonyms
  • CEACAM6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); NCA; carcinoembryonic antigen-related cell adhesion molecule 6; CD66c; normal cross-reacting antigen; non-specific crossreacting antigen; CEAL;

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