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Recombinant Human Antibody is against Human 4-1BB, expressed in Chinese Hamster Ovary cells(CHO)
Human IgG4 - kappa
Ectodomain of human 4-1BB recombinant protein.
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
Immunoglobulin G4-kappa, anti-[Homo sapiens TNFRSF9 (tumor necrosis factor receptor superfamily member 9, 4-1BB, T cell antigen ILA, CD137)], Homo sapiens monoclonal antibody
Predicted N terminal
H chain: QVQLQQW; L Chain: EIVLTQS
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Store at -20°C. Avoid multiple freeze/thaw cycles.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.