ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-604	Dde Biotin-PEG4-azide	1802907-93-2		695.9	95%		Inquiry
ADC-L-605	Dde Biotin-PEG4-Picolyl azide	2055048-42-3		816	95%		Inquiry
ADC-L-606	Diazo Biotin-PEG3-N3	1339202-33-3		711.8	95%		Inquiry
ADC-L-607	N-(Azido-PEG4)-biocytin	2055042-70-9		645.8	95%		Inquiry
ADC-L-608	DADPS Biotin Azide	1260247-50-4		886.2	95%		Inquiry
ADC-L-609	Biotin-PEG2-C4-alkyne	1011268-28-2		468.6	95%		Inquiry
ADC-L-610	Biotin-PEG4-alkyne	1458576-00-5		457.6	95%		Inquiry
ADC-L-611	Dde Biotin-PEG4-alkyne	1802908-00-4		650.8	95%		Inquiry
ADC-L-612	Diazo Biotin-PEG3-alkyne	1884349-58-9		796	95%		Inquiry
ADC-L-613	N-(Propargyl-PEG4)-biocytin	2055042-71-0		614.8	95%		Inquiry
ADC-L-614	PC-Biotin-PEG4-PEG4-alkyne			927.1	95%		Inquiry
ADC-L-615	DADPS Biotin Alykne	2241685-22-1		827.1	95%		Inquiry
ADC-L-616	Bis-Biotin-PEG23	293298-36-9		1525.9	95%		Inquiry
ADC-L-618	Diazo Biotin-PEG3-DBCO			973.2	95%		Inquiry
ADC-L-620	DBCO-PEG4-Desthiobiotin	2032788-37-5		719.9	95%		Inquiry
ADC-L-621	Dde Biotin-PEG4-DBCO	1807512-43-1		872.1	95%		Inquiry
ADC-L-622	PC DBCO-PEG3-biotin			1002.2	95%		Inquiry
ADC-L-624	Biotin-hydrazide	66640-86-6		258.3	95%		Inquiry
ADC-L-625	Biotin-PEG3-hydrazide	1381861-94-4		461.6	95%		Inquiry
ADC-L-626	Biotin-PEG5-NH-Boc	189209-28-7		606.8	95%		Inquiry