ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-647	Mal-PEG1-t-butyl ester	810677-16-8		269.3	95%		Inquiry
ADC-L-648	Mal-PEG2-alcohol	34321-81-8		185.2	95%		Inquiry
ADC-L-649	Mal-PEG2-amine TFA salt	660843-22-1		228.3	95%		Inquiry
ADC-L-650	Mal-PEG2-NH-Boc	660843-21-0		328.4	95%		Inquiry
ADC-L-651	Mal-amido-PEG9-NHBoc	2182602-20-4		707.8	95%		Inquiry
ADC-L-652	Maleimide-amido-PEG-Acid (PEG1-PEGn)	756525-98-1		328.3	95%		Inquiry
ADC-L-653	Mal-amido-PEG9-amine TFA salt	2182602-22-6		607.7	95%		Inquiry
ADC-L-654	Maleimide-amido-PEG-NHS (PEG1-PEGn)	955094-26-5		425.4	95%		Inquiry
ADC-L-655	Mal-amido-PEG2-TFP ester	1431291-44-9		476.4	95%		Inquiry
ADC-L-656	Maleimide-amido-PEG-methyl (PEG1-PEGn)	1263044-81-0		358.4	95%		Inquiry
ADC-L-657	3-Maleimidopropionic acid	7423-55-4		169.1	95%		Inquiry
ADC-L-658	4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid	57078-98-5		183.2	95%		Inquiry
ADC-L-659	5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid	57078-99-6		197.2	95%		Inquiry
ADC-L-660	6-Maleimidocaproic acid	55750-53-3		211.2	95%		Inquiry
ADC-L-661	4-((2,5-Dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexanecarboxylic acid	64987-82-2		237.3	95%		Inquiry
ADC-L-662	1-(2-Aminoethyl)-1H-pyrrole-2,5-dione TFA salt	146474-00-2		140.1	95%		Inquiry
ADC-L-663	Maleimide-C6-amine TFA salt	731862-92-3		196.3	95%		Inquiry
ADC-L-664	Mal-PEG1-Bromide	1823885-81-9		248.1	95%		Inquiry
ADC-L-665	3-Maleimido-propionic NHS ester	55750-62-4		266.2	95%		Inquiry
ADC-L-666	Maleimide-heptanoic NHS ester	55750-63-5		308.3	95%		Inquiry