ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-710	TCO-PEG8-TFP ester	2353410-06-5		741.8	95%		Inquiry
ADC-L-711	TCO-PNB ester	1438415-89-4		291.3	95%		Inquiry
ADC-L-712	TCO-PEG-amine (PEG1-PEGn)	2141981-87-3		300.4	95%		Inquiry
ADC-L-713	TCO-PEG4-biotin	2183440-30-2		614.8	95%		Inquiry
ADC-L-714	TCO-PEG4-DBCO	1801863-88-6		675.8	95%		Inquiry
ADC-L-715	TCO-PEG9-maleimide	2183440-37-9		759.9	95%		Inquiry
ADC-L-716	TCO-PEG3-triethoxysilane	2250217-32-2		576.8	95%		Inquiry
ADC-L-717	TCO-PEG-TCO (PEG1-PEGn)	2243569-22-2		496.6	95%		Inquiry
ADC-L-718	Gly-Gly-Gly-PEG3-TCO	2353409-81-9		515.6	95%		Inquiry
ADC-L-719	Methyltetrazine-PEG4-amine	1802908-05-9		363.4	95%		Inquiry
ADC-L-720	Methyltetrazine-PEG-acid (PEG1-PEGn)	1802907-91-0		436.5	95%		Inquiry
ADC-L-721	Tetrazine-NHS ester	1616668-55-3		313.3	95%		Inquiry
ADC-L-722	Methyltetrazine-NHS ester	1644644-96-1		327.3	95%		Inquiry
ADC-L-723	Methyltetrazine-Sulfo-NHS ester	1821017-46-2		429.3	95%		Inquiry
ADC-L-724	Tetrazine-PEG5-NHS ester	1682653-80-0		604.6	95%		Inquiry
ADC-L-725	Methyltetrazine-PEG5-NHS ester	1802907-92-1		533.5	95%		Inquiry
ADC-L-726	Methyltetrazine-PEG8-PFP ester	2353409-49-9		778.7	95%		Inquiry
ADC-L-727	Methyltetrazine-PEG5-alkyne	1802907-97-6		402.5	95%		Inquiry
ADC-L-728	Methyltetrazine-amido-PEG5-alkyne	2322322-23-4		487.6	95%		Inquiry
ADC-L-729	Methyltetrazine-PEG4-N3	1802908-04-8		389.4	95%		Inquiry