ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-771	N-Benzyl-N-bis(PEG1-OH)	119580-47-1		283.4	95%		Inquiry
ADC-L-772	Bis-PEG1-PFP ester	1807539-02-1		494.2	95%		Inquiry
ADC-L-773	2-(t-Butoxycarbonylamido)-1,3-bis(PFP-oxycarbonylethoxy)propane	1807521-01-2		667.5	95%		Inquiry
ADC-L-774	Thiol-PEG-acid (PEG1-PEGn)	1347750-82-6		238.3	95%		Inquiry
ADC-L-775	Thiol-PEG3-t-butyl ester	1446282-39-8		294.4	95%		Inquiry
ADC-L-777	Thiol-PEG3-phosphonic acid	1360716-36-4		274.3	95%		Inquiry
ADC-L-778	m-PEG6-thiol	441771-60-4		312.4	95%		Inquiry
ADC-L-780	Lipoamido-PEG-acid (PEG1-PEGn)	1314378-10-3		453.6	95%		Inquiry
ADC-L-781	Lipoamido-PEG2-alcohol	1674386-82-3		337.5	95%		Inquiry
ADC-L-782	Lipoamido-PEG3-N3	890016-39-4		406.6	95%		Inquiry
ADC-L-783	Lipoamido-PEG3-maleimide	1314378-19-2		559.7	95%		Inquiry
ADC-L-784	S-acetyl-PEG-alcohol (PEG1-PEGn)	153870-20-3		208.3	95%		Inquiry
ADC-L-785	S-acetyl-PEG-t-butyl ester (PEG1-PEGn)	1820641-93-7		292.4	95%		Inquiry
ADC-L-786	S-acetyl-PEG3-acid	1421933-33-6		278.4	95%		Inquiry
ADC-L-787	S-acetyl-PEG4-alkyne	1422540-88-2		290.4	95%		Inquiry
ADC-L-788	S-acetyl-PEG3-N3	1310827-26-9		277.3	95%		Inquiry
ADC-L-789	S-acetyl-PEG6-tosyl	1818294-25-5		494.6	95%		Inquiry
ADC-L-790	SPDP-PEG-acid (PEG1-PEGn)	581065-97-6		462.6	95%		Inquiry
ADC-L-791	SPDP-PEG-NHS-ester (PEG1-PEGn)	1334177-95-5		559.7	95%		Inquiry
ADC-L-792	(2-pyridyldithio)-PEG4-alcohol	851961-99-4		319.4	95%		Inquiry