ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-Y0307	Biotin-PEG12-NHS ester	365441-71-0		941.1	95%		Inquiry
ADC-L-Y0308	Desthiobiotin-PEG3-NHS ester	2411681-92-8		514.6	95%		Inquiry
ADC-L-Y0310	Biotin-PEG4-alcohol	1217609-84-1		419.5	95%		Inquiry
ADC-L-Y0311	Biotin-PEG6-alcohol	906099-89-6		507.7	95%		Inquiry
ADC-L-Y0312	Biotin-PEG8-alcohol	2182601-20-1		595.8	95%		Inquiry
ADC-L-Y0314	Biotin-PEG3-amine	359860-27-8		418.6	95%		Inquiry
ADC-L-Y0315	Biotin-PEG4-amine	663171-32-2		462.6	95%		Inquiry
ADC-L-Y0316	Biotin-PEG5-amine	113072-75-6		506.7	95%		Inquiry
ADC-L-Y0317	Biotin-PEG6-amine			550.7	95%		Inquiry
ADC-L-Y0318	Biotin-PEG7-amine	1334172-76-7		594.8	95%		Inquiry
ADC-L-Y0319	Biotin-PEG8-amine	2183447-27-8		638.8	95%		Inquiry
ADC-L-Y0320	Biotin-PEG11-amine	1418022-42-0		771	95%		Inquiry
ADC-L-Y0321	Biotin-PEG23-amine	604786-74-5		1299.6	95%		Inquiry
ADC-L-Y0323	Biotin-PEG4-TFP ester			639.7	95%		Inquiry
ADC-L-Y0324	Biotin-PEG12-TFP ester	2055105-33-2		992.1	95%		Inquiry
ADC-L-Y0325	Biotin-PEG24-TFP ester	2055105-33-2		1520.7	95%		Inquiry
ADC-L-Y0326	Biotin-PEG36-PFP ester	2353409-51-3		2067.4	95%		Inquiry
ADC-L-Y0327	Biotin-PFP ester	120550-35-8		410.4	95%		Inquiry
ADC-L-Y0328	Biotin-PEG2-Mal	305372-39-8		525.6	95%		Inquiry
ADC-L-Y0330	Biotin-PEG6-Mal	1808990-66-0		701.8	95%		Inquiry