ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-Y0396	Bis-PEG25-acid	51178-68-8		1219.4	95%		Inquiry
ADC-L-Y0397	Bis-PEG29-acid	51178-68-8		1395.6	95%		Inquiry
ADC-L-Y0398	PEG2-(CH2CO2H)2	23243-68-7		178.1	95%		Inquiry
ADC-L-Y0399	PEG3-(CH2CO2H)2	13887-98-4		222.2	95%		Inquiry
ADC-L-Y0400	PEG5-(CH2CO2H)2	77855-75-5		310.3	95%		Inquiry
ADC-L-Y0401	PEG6-(CH2CO2H)2	77855-76-6		354.4	95%		Inquiry
ADC-L-Y0408	Bis-PEG6-NHS ester	1526718-98-8		576.6	95%		Inquiry
ADC-L-Y0409	Bis-PEG7-NHS ester	1334170-02-3		620.6	95%		Inquiry
ADC-L-Y0411	Bis-PEG10-NHS ester	1008402-79-6		752.8	95%		Inquiry
ADC-L-Y0412	Bis-PEG11-NHS ester	123502-57-8		796.8	95%		Inquiry
ADC-L-Y0413	Bis-PEG13-NHS ester	1008402-79-6		884.9	95%		Inquiry
ADC-L-Y0414	Bis-PEG17-NHS ester	1008402-79-6		1061.1	95%		Inquiry
ADC-L-Y0415	Bis-PEG21-NHS ester	1008402-79-6		1237.4	95%		Inquiry
ADC-L-Y0416	Bis-PEG25-NHS ester	1008402-79-6		1413.6	95%		Inquiry
ADC-L-Y0417	Di(N-succinimidyl)adipate	59156-70-6		340.3	95%		Inquiry
ADC-L-Y0418	EGS Crosslinker	70539-42-3		456.4	95%		Inquiry
ADC-L-Y0420	t-Boc-N-amido-PEG2-acid	1365655-91-9		277.3	95%		Inquiry
ADC-L-Y0421	t-Boc-N-amido-PEG3-acid	1347750-75-7		321.4	95%		Inquiry
ADC-L-Y0422	t-Boc-N-amido-PEG4-acid	756525-91-4		365.4	95%		Inquiry
ADC-L-Y0423	t-Boc-N-amido-PEG5-acid	1347750-78-0		409.5	95%		Inquiry