ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-Y0331	Biotin-PEG11-Mal	1334172-60-9		922.1	95%		Inquiry
ADC-L-Y0333	Biotin-PEG3-azide	875770-34-6		444.6	95%		Inquiry
ADC-L-Y0334	Biotin-PEG4-azide	1309649-57-7		488.6	95%		Inquiry
ADC-L-Y0335	Biotin-PEG5-azide	1163732-89-5		532.7	95%		Inquiry
ADC-L-Y0336	Biotin-PEG6-azide	1085938-09-5		576.7	95%		Inquiry
ADC-L-Y0337	Biotin-PEG7-azide	1334172-75-6		620.8	95%		Inquiry
ADC-L-Y0338	Biotin-PEG8-azide			664.8	95%		Inquiry
ADC-L-Y0339	Biotin-PEG11-azide	956494-20-5		797	95%		Inquiry
ADC-L-Y0340	Biotin-PEG23-azide	956494-20-5		1325.6	95%		Inquiry
ADC-L-Y0342	Biotin-Azide	1006592-62-6		615.8	95%		Inquiry
ADC-L-Y0346	Diazo Biotin-PEG3-azide	1339202-33-3		711.8	95%		Inquiry
ADC-L-Y0348	UV Cleavable Biotin-PEG2-Azide	1654739-36-2		781.9	95%		Inquiry
ADC-L-Y0352	Biotin-Alkyne	1006592-45-5		528.7	95%		Inquiry
ADC-L-Y0356	UV Cleavable Biotin-PEG2-alkyne			736.9	95%		Inquiry
ADC-L-Y0361	Biotin hydrazide	66640-86-6		258.3	95%		Inquiry
ADC-L-Y0363	Biotin-PEG4-hydrazide	756525-97-0		505.6	95%		Inquiry
ADC-L-Y0364	Biotin-PEG6-hydrazide			593.7	95%		Inquiry
ADC-L-Y0365	Biotin-PEG12-hydrazide			858.1	95%		Inquiry
ADC-L-Y0366	Biotin-PEG2-NH-Boc	175885-18-4		474.6	95%		Inquiry
ADC-L-Y0368	Biotin-PEG6-NH-Boc	1292268-20-2		650.8	95%		Inquiry