Repeatability Evaluation Service for Exosome Product
Exosome product repeatability refers to the consistency of properties and characteristics between different batches of the same exosome product, which is very important for product reliability and subsequent large-scale experiments. Creative Biolabs specializes in providing repeatability evaluation services based on exosome products, providing more reliable technical support for exosome-related research and clinical applications.
Good Repeatability of Exosome Products is the Most Basic Guarantee
The process of preparing and characterizing exosomes is a rather intricate one, and the absence of standardized quality control measures has compounded this complexity. Hence, it becomes imperative to assess and validate the inter-batch consistency of these products, thereby ensuring their overall quality. The salient benefit of achieving repeatability in exosome products is manifold.
Repeatability Evaluation Service of Exosome Product at Creative Biolabs
Consistently adhering to the service concept of high quality and customer first, Creative Biolabs has the ability to help customers evaluate the batch-to-batch consistency of exosome products by providing the following professional technical services.
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Evaluation method
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Evaluation content
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Nanoparticle Tracking Analysis
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Use laser light scattering technology to analyze the size, quantity, and concentration of exosomes.
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Transmission Electron Microscopy
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Use electron microscopy techniques to observe the morphology, structure, and size of exosomes.
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Western Blotting
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Use immunological-based hybridization to quantify specific proteins in exosomes, such as CD9, CD63, and CD81.
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Nanoparticle Flow Cytometry
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Use lasers and detectors to measure the physical properties of individual exosomes in the fluid stream as well as the quantity of exosome surface markers.
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Enzyme-linked Immunosorbent Assay
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Use enzyme-labeled technology to detect the relative concentration of specific proteins in exosomes.
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Mass Spectrometry
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Use mass spectrometry to analyze the RNA or protein composition in the exosomes.
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Real-time Polymerase Chain Reaction
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Use gene amplification technology to detect the relative content of specific RNAs in exosomes.
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High-Performance Liquid Chromatography
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Separate and analyze loaded therapeutic drugs in exosomes, such as paclitaxel, peptides, chitosan, etc.
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Statistical Analysis
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Use correlation analysis methods to assess the consistency of different batches of exosome products.
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Other possible evaluation methods
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Published Results of Stability Evaluation of Exosome Product
Fig. 1 Spearman correlation matrix between EV batches to assess consistency using the background-subtracted. (Korchak, 20 23)
Information You Need to Provide
If you want to evaluate the repeatability of your exosome products, please contact us and leave a message below.
Product information: This includes the source of exosomes, extraction method, storage method, etc. This information can help us better understand the characteristics of the products.
Reference
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Korchak, JA.; Wiest, EF.; et al. How do we assess batch-to-batch consistency between extracellular vesicle products? Transfusion. 2023. 63(2):279-287.
For Research Use Only. Cannot be used by patients.
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