Because exosomes (Exos) are considered as a potential therapeutic tool and have been widely recognized in many clinical trials. Despite their many potentials, Exos also have safety concerns that may affect their clinical application. Therefore, it is very important to evaluate the safety of Exo products. Creative Biolabs pays special attention to the safety of Exo products in subsequent trials.

Fig. 1 Safety evaluation of hiPSC-exosomes at the cellular level. (Gu, 2022)

Highlight Safety Issues of Exosome (Exo) Product

Exos have shown low immunogenicity in clinical applications. However, as a new type of biological product, any drug or cosmetic needs a comprehensive safety evaluation to ensure its safety and reliability for the human body. Therefore, it is very important to evaluate the safety of Exo products.

Therefore, the safety evaluation of Exo products can ensure that the quality and safety of the products meet the requirements of later in vivo tests and avoid possible safety problems.

Safety Evaluation Service of Different Type Exo Products at Creative Biolabs

If the safety of Exo drugs cannot be fully guaranteed, it may have adverse effects on human health. At the same time, the use of Exos in the skin care industry also requires safety evaluation to ensure that they can be safely and effectively applied to human skin.

Therefore, Creative Biolabs launched the safety evaluation service of candidate Exo drug and the safety evaluation service of skincare Exo, aiming to provide customers with comprehensive and professional Exo safety evaluation solutions. The service covers a variety of safety evaluation methods and experimental techniques, including cytotoxicity testing, in vivo toxicity testing in mice, immunogenicity testing, etc., to ensure the safety and reliability of candidate Exo drugs and Exo skin care products. If you need to make a preliminary safety evaluation of Exo products during the development process, please contact us.

Reference

1. Gu, Z.; Yin, Z.; et al. Safety and biodistribution of exosomes derived from human induced pluripotent stem cells. Frontiers in Bioengineering and Biotechnology. 2022. 10:949724.

• Stability Evaluation
• Repeatability Evaluation
• Specificity Evaluation
• Production Efficiency Evaluation
• Purity Evaluation