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Magic™ Membrane Protein Human OLR1 (Oxidized low density lipoprotein receptor 1) Expressed in NS0 for Antibody Discovery, Partial (61-273aa) (CAT#: MPX0230K)

Datasheet
This product is a 25.5 kDa Human OLR1 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • OLR1
  • Protein Length
  • Partial (61-273aa)
  • Protein Class
  • Receptor; Immunity
  • Molecular Weight
  • 25.5 kDa
  • TMD
  • 1
  • Sequence
  • SQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESEN
    ELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIW
    HGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSF
    PFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGA
    VYAENCILAAFSICQKKANLRAQ

Product Description

  • Expression Systems
  • NS0
  • Tag
  • 9xHis tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.10 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.

Target

  • Target Protein
  • OLR1
  • Full Name
  • Oxidized low density lipoprotein receptor 1
  • Introduction
  • This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • OLR1; LOX1; LOXIN; SLOX1; CLEC8A; SCARE1; oxidized low-density lipoprotein receptor 1; C-type lectin domain family 8 member A; hLOX-1; lectin-type oxidized LDL receptor 1; ox LDL receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low-density lipoprotein receptor 1, soluble form; scavenger receptor class E, member 1; Oxidized low density lipoprotein receptor 1

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