ADC Linker Products

Product Overview Related Services Scientific Resources Quick Links Product List

Product Overview

Creative Biolabs offers a variety of chemically versatile linker molecules to facilitate antibody-drug conjugate (ADC) development projects. All chemical linkers are of >95% purity and they are the basic building blocks for a successful ADC. Linkers facilitate the conjugation of ADC toxins to antibodies and in the meantime, they also dictate the release mechanism of an ADC. Proper linker selection will not only ease the process of obtaining the conjugate but also help enhance the chemical and serum stability of the ADC. Creative Biolabs carries a series of cleavable linkers (pH-sensitive linkers, disulfide linker, peptide linkers, β-glucuronide linkers), non-cleavable linkers, and intermediate linker modules. In the meantime, we also offer the services in the DrugLnk synthesis platform to prepare customized linkers with unique structures.

ADC Linker Services

Creative Biolabs offers a comprehensive "DrugLnk" linker module designed to cater to the diverse needs of antibody-drug conjugate (ADC) development. This module focuses on the design and preparation of various types of linkers, tailored to their specific drug release mechanisms. Clients can choose from a range of linker types:

Leveraging an advanced synthetic chemistry platform along with an extensive inventory of toxins, linkers, and drug-linker sets, "DrugLnk" at Creative Biolabs enables our skilled chemists to provide specialized services.

(1) Design linkers with optimal size
(2) Select linkers with suitable release mechanism
(3) Engineer linkers with compatible conjugation chemistry
(4) Synthesize customized linkers
(5) Modify payload drug
(6) Design synthesis routes
(7) Synthesize customized drug-linker complexes

Please feel free to contact us for more information about our ADC linker services.

Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

Global Antibody-drug Conjugate (ADC) Clinical Trial ReviewGlobal Antibody-drug Conjugate (ADC) Clinical Trial Review 2018.3

Creative Biolabs ADC Product Brochure

Protocol

Quick Links

ADC Toxins

Drug-linker Complexes

Customized ADCs

Anti-Ab ADCs

Product List

Catalog	Product name	CAS NO	Structure	Molecular Weight	Purity	Data sheet	Inquiry
ADC-L-Y0480	Bromo-PEG4-acid	1393330-38-5		329.2	95%		Inquiry
ADC-L-Y0481	Bromo-PEG5-acid	1817735-27-5		373.2	95%		Inquiry
ADC-L-Y0482	Bromo-PEG1-CH2CO2H	1135131-50-8		183	95%		Inquiry
ADC-L-Y0483	Bromo-PEG3-CH2CO2H	1346502-15-5		271.1	95%		Inquiry
ADC-L-Y0485	Bromo-PEG2-t-butyl ester	1381861-91-1		297.2	95%		Inquiry
ADC-L-Y0486	Bromo-PEG3-t-butyl ester	782475-37-0		341.2	95%		Inquiry
ADC-L-Y0487	Bromo-PEG4-t-butyl ester	564476-32-0		385.3	95%		Inquiry
ADC-L-Y0488	Bromo-PEG5-t-butyl ester	1415800-38-2		429.4	95%		Inquiry
ADC-L-Y0489	Bromo-PEG6-t-butyl ester	1393330-41-0		473.4	95%		Inquiry
ADC-L-Y0490	Bromo-PEG8-t-butyl ester	1623792-00-6		561.5	95%		Inquiry
ADC-L-Y0491	Bromo-PEG12-t-butyl ester			873.7	95%		Inquiry
ADC-L-Y0492	Bromo-PEG24-t-butyl ester			1266.4	95%		Inquiry
ADC-L-Y0494	Bromo-PEG2-CH2CO2tBu	1807518-63-3		283.2	95%		Inquiry
ADC-L-Y0495	Bromo-PEG3-CH2CO2tBu	2100306-71-4		327.2	95%		Inquiry
ADC-L-Y0496	Bromo-PEG4-CH2CO2tBu	1807505-29-8		371.3	95%		Inquiry
ADC-L-Y0497	Bromo-PEG2-methyl ester			255.1	95%		Inquiry
ADC-L-Y0498	Bromo-PEG5-alcohol	957205-14-0		301.2	95%		Inquiry
ADC-L-Y0500	Bromo-PEG2-azide	530151-56-5		238.1	95%		Inquiry
ADC-L-Y0501	Bromo-PEG3-azide	1446282-43-4		282.1	95%		Inquiry
ADC-L-Y0502	Bromo-PEG4-azide	1951439-37-4		326.2	95%		Inquiry