Human DLK1 antibody pair set for sandwich ELISA useCapture Antibody: Monoclonal IgGDetection Antibody: Unconjugated-Rabbit Monoclonal IgG
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Antigen Detail | |
|---|---|
| Target | DLK1 |
| Description | Protein delta homolog 1 is a protein encoded by the DLK1 gene in humans. It is expressed as a transmembrane protein, but the soluble form that can be cleaved by ADAM17 is active in inhibiting adipogenesis and differentiation of preadipocytes into adipocytes. It is a member of the EGF-like homologous protein family. This gene is part of the Dlk1-DIO3 imprinting control region and is a gene involved in the epigenetic process, which results in some genes being regulated according to their parental origin. Such imprinted genes are necessary for placenta formation and the development of cell lineages (such as those derived from mesoderm and ectoderm). |
| Species Reactivity | Human |
Capture Antibody | |
|---|---|
| Capture Clonality | Monoclonal |
| Host Species | Rabbit |
| Clone | IV01388 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, containing 0.1% Proclin 300 |
| Application | ELISA |
Detection Antibody | |
|---|---|
| Det-Clonality | Monoclonal |
| Host Species | Rabbit |
| Conjugation | Unconjugated |
| Clone | RD10460 |
| Isotype | IgG |
| Purification | Affinity Chromatography |
| Buffer | PBS, pH 7.4, BSA and Azide free |
General Product Property | |
|---|---|
| Product Overview | Human DLK1 antibody pair set for sandwich ELISA use Capture Antibody: Monoclonal IgG Detection Antibody: Unconjugated-Rabbit Monoclonal IgG |
| Specificity | Both the capture and the detection antibodies in this set react with Human DLK1 . |
| Range | 62.5 pg/mL-4000 pg/mL |
| Research Area | Immunology; Cell Biology; Cancer; Inflammation |
| Application | ELISA |
| Application Notes | Optimal dilutions should be determined experimentally by the user. |
| Form | Liquid |
| Storage | Avoid repeated freeze/thaw cycles. Store at 2-8°C for short term. Aliquot and store at -20°C for long term storage. |
| Size | 1 Set |
| Sample Type | Plasma; Serum; Cell Culture Supernatant |
| Usage Statement | Available for Research Use Only. Not for use in therapeutic or diagnostic applications. |
Target Overview | |
|---|---|
| Gene Symbol | DLK1 |
| Full Name | DLK1 |
| Background | Protein delta homolog 1 is a protein encoded by the DLK1 gene in humans. It is expressed as a transmembrane protein, but the soluble form that can be cleaved by ADAM17 is active in inhibiting adipogenesis and differentiation of preadipocytes into adipocytes. It is a member of the EGF-like homologous protein family. This gene is part of the Dlk1-DIO3 imprinting control region and is a gene involved in the epigenetic process, which results in some genes being regulated according to their parental origin. Such imprinted genes are necessary for placenta formation and the development of cell lineages (such as those derived from mesoderm and ectoderm). |
| Alternative Names | DLK1; DLK; DLK-1; Delta1; FA1; PREF1; Pref-1; ZOG; pG2; AW742678; DlkI; Ly107; Peg9; SCP1; delta like non-canonical Notch ligand 1 |
| GeneCards | DLK1 |
| HGNC | 2907 |
| Ensembl | ENSG00000185559 |
| OMIM | 176290 |
| Involvement in Disease | Diseases associated with DLK1 include Temple Syndrome and Idiopathic Central Precocious Puberty. |
| Function | May have a role in neuroendocrine differentiation. |
| Related Pathways | Its related pathways are Signaling by GPCR and Notch Signaling Pathway (WikiPathways). |
For Research Use Only.
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