Introduction
Harness the power of your genetic code with our state-of-the-art genome-level analysis service. Combining proprietary AI-driven bioinformatics with multi-omics integration, we decode DNA with clinical-grade precision, uncovering actionable insights into disease risk, therapeutic responses, and evolutionary biology. From rare variant discovery to population-scale genomic epidemiology, our platform delivers scalable, secure, and lightning-fast results. Trust our team of computational biologists to transform raw genomic data into strategic breakthroughs for drug development, precision oncology, or conservation genomics. Whether you're investigating rare diseases, optimizing crop resilience, or advancing precision medicine, our services provide the clarity and confidence you need to drive breakthroughs.
Technology Catalog
| Technology | Introduction | Advantages | Applications |
|---|---|---|---|
| DNA Sequencing Services | Analyzes DNA fragment sequences (A, T, C, G) using Sanger or NGS. | High-throughput, cost-effective, and scalable for whole genomes or targeted regions. | Genetic research, disease diagnosis, forensic analysis, and evolutionary studies. |
| RNA Sequencing Services | Quantifies and profiles RNA transcripts via NGS to study gene expression. | Full transcriptome coverage, detects low-abundance transcripts, and identifies novel isoforms. | Cancer research, drug discovery, and understanding disease mechanisms. |
| Microarray Services | Hybridizes labeled DNA/cDNA probes to solid-surface arrays for gene expression analysis. | High-throughput, cost-efficient, and multiplexed detection of thousands of genes. | Genetic profiling, SNP discovery, and biomarker identification. |
| FISH Services | Fluorescently labels DNA probes to detect specific sequences in chromosomes/cells. | High-resolution spatial mapping visualizes structural variations. | Cytogenetics, cancer diagnostics, and prenatal screening. |
| PCR Services | Amplifies specific DNA targets using thermostable polymerases and primers. | Highly sensitive, rapid, and specific for low-abundance DNA. | Infectious disease detection, genetic testing, and cloning. |
| DNA Restriction Enzyme Analysis | Cuts DNA at specific sites using restriction enzymes to map genomic structures. | Precise DNA fragmentation aids in genome mapping and cloning. | Genotyping, recombinant DNA technology, and phylogenetic studies. |
| Single-Strand Conformation Polymorphism Analysis | Detects single-base mutations via single-strand DNA conformational differences. | Simple, cost-effective, and sensitive to point mutations. | Cancer research, microbial genetics, and inherited disease screening. |
| Single Nucleotide Polymorphism Analysis | Identifies single-nucleotide polymorphisms (SNPs) as genetic markers. | High-density genome coverage enables GWAS and pharmacogenomics. | Population genetics, personalized medicine, and agricultural breeding. |
| Diagnosis of Point Mutation | Identifies single-base changes in DNA/RNA linked to diseases like cancer. | High accuracy, critical for targeted therapies and genetic counseling. | Oncology, inherited disorders (e.g., cystic fibrosis), and infectious disease surveillance. |
Service Workflow
Partner with our scientific experts to co-design your study, aligning technical approaches with research objectives. We specialize in translating concepts into actionable workflows, accommodating diverse sample types and output requirements.
Support for all major biological matrices, including blood, tissue, saliva, and cell-free nucleic acids. All samples undergo rigorous quality assessment within 24 hours, with metrics validated for integrity, purity, and fragmentation levels.
- Genomic Profiling: Scalable solutions from rapid targeted sequencing to deep whole-genome characterization.
- Transcriptomic Workflows: Expedited RNA analysis with uniform coverage and strand-specific resolution.
- Functional Genomics: Comprehensive screening support, including guide efficiency validation and phenotypic outcome tracking.
- Dynamic visualization portals with customizable data layers, statistical overlays, and exportable graphics.
- Expert-led result interpretation sessions, including manuscript figure preparation and statistical reanalysis support.
Applications
Oncology Research
- Tumor Heterogeneity Mapping: Unravel clonal evolution and therapeutic vulnerabilities through single-cell and spatial multi-omics (DNA/RNA/protein).
- Resistance Mechanism Profiling: Identify dynamic drivers of treatment failure via longitudinal ctDNA monitoring and ex vivo functional screens.
Biomarker Discovery
- Targetable Biomarker Identification: Prioritize actionable variants using AI-driven prioritization pipelines and in vitro/in vivo validation models.
- Predictive Signature Development: Construct polygenic risk scores and treatment response classifiers with cross-cohort machine learning.
Rare Disease Research
- Causal Variant Triangulation: Combine WGS, RNA-Seq, and epigenomic data to resolve undiagnosed cases through integrative variant filtering.
- Pathogenic Pathway Reconstruction: Map disease mechanisms using 3D chromatin interaction analysis.
Pharmacogenomic Innovation
- Response Architecture Mapping: Deconvolute polygenic drug efficacy/toxicity signals in preclinical models.
- Target Deconvolution: Validate druggable targets using multi-omics endpoint analysis.
Service Highlights
- Custom Panels: Tailor gene panels to match your study's precise scope, whether targeting a handful of critical loci or broad genomic landscapes. Our flexible design tools accommodate projects of any scale, from hypothesis-driven candidate gene studies to population-level association screens.
- AI Integration: Enhance analysis with AI-driven genomic tools that predict splicing patterns, assess variant impacts, and prioritize functional elements. These algorithms accelerate data interpretation while maintaining accuracy, ensuring robust insights even in complex regulatory regions.
- Data Security: Protect sensitive research with enterprise-grade security protocols, including encrypted data storage, strict access controls, and immutable audit trails. Our infrastructure exceeds global regulatory standards, safeguarding intellectual property and participant confidentiality.
- Rush Options: Accelerate time-sensitive projects through prioritized sequencing and analysis pipelines. Ideal for urgent clinical studies, disease outbreak investigations, or competitive grant deadlines, our STAT services maintain quality while compressing timelines.
FAQs
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What types of biological samples do you accept for analysis?
Accommodate diverse biological matrices (DNA/RNA/proteins/cells) with input volumes optimized for projects spanning single-gene studies to genome-scale analyses.
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How do you ensure the accuracy and reliability of my data?
Rigorous multi-tier QC protocol encompassing pre-processing purity checks, analytical-phase contamination monitoring, and post-hoc validation via third-party tools (e.g., FASTQC) plus manual expert review.
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Can you analyze genetic material from non-traditional organisms?
Yes! We specialize in non-model species, from bacterial pathogens to plant genomes. Our services include de novo genome assembly for organisms lacking reference sequences.
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How do you handle large-scale data analysis efficiently?
We mitigate bottlenecks through:
- Automated Pipelines: Scalable infrastructure for alignment, variant calling, and expression profiling.
- Expert Oversight: PhD-level bioinformaticians validate results and refine analyses.
- Collaborative Tools: Cloud-based workspaces for real-time result sharing and annotation.
At Creative Biolabs, we don't just analyze genes-we empower breakthroughs. With unmatched flexibility in sample handling, military-grade data integrity, and lightning-fast turnarounds, your genomic challenges become our solved equations. Whether deciphering rare variants, profiling non-model organisms, or integrating multi-omics layers, our team ensures every base pair tells a story. Request a customized quote today!
For Research Use Only.
